Regeneration of dentin-pulp complex by using dental pulp stem cells in dog

Pulp Regeneration by Harnessing Dental Pulp Stem Cells

The Effects of Platelet‐Derived Growth Factor‐BB on Human Dental Pulp Stem Cells Mediated Dentin‐Pulp Complex Regeneration

Dentin-pulp complex regeneration is a promising alternative treatment for the irreversible pulpitis caused by tooth trauma or dental caries. This process mainly relies on the recruitment of endogenous or the transplanted dental pulp stem cells (DPSCs) to guide dentin-pulp tissue formation. Platelet-derived growth factor (PDGF), a well-known potent mitogenic, angiogenic, and chemoattractive agen...

Stem Cells of the Dental Pulp

 Dental Pulp Stem Cells (DPSCs) can be found within the cell rich zone of dental pulp. These stem cells, under specific stimuli, differentiate into many cell types which have wide therapeutic applications.   The dental stem cells are derived from both deciduous and permanent teeth. The viable dental stem cells are very simple to collect, without any mortality and morbidity. Dental pulp stem c...

Dentin-Pulp Complex Regeneration Therapy Following Pulp Amputation

Dental pulp, which is surrounded by hard tissue (dentin and enamel), consists of pulp cells, odontoblasts, endothelial cells, neurons, immune system cells, and the extracellular matrix, and plays key roles in maintaining the function of healthy teeth [1]. Via the apical foramen of tooth, blood vessels supply nutrients to the tooth and remove waste products, and neural network warns for harmful ...

Transdifferentiation of Human Dental Pulp Stem Cells Into Oligoprogenitor Cells

Introduction: The nerve fibers in central nervous system are surrounded by myelin sheet  which is formed by oligodendrocytes. Cell therapy based on oligodendrocytes and their precursors transplantation can hold a promising alternative treatment for myelin sheet repair in demyelinating diseases. Methods: Human Dental Pulp Stem Cells (hDPSCs) are noninvasive, autologous and easy available s...